منابع مشابه
E VALUATION OF ADENYLATE CYCLASE ACTIVITY IN MITRAL VALVE PROLAPSE
The term mitral valve prolapse (MVP) is used for a particular subset of patients with hyperadrenergic dysautonomia. It occurs when part of a leaflet or both leaflets of the mitral valve extend above the plane of the atrioventricular junction during ventricular systole. The adenylate cyclase activity in MVP dys-autonomia was studied by extraction of enzyme from the erythrocytes from 62 norma...
متن کاملMouse neuroblastoma adenylate cyclase. Adenosine and adenosine analogues as potent effectors of adenylate cyclase activity.
1. Intact mouse neuroblastoma NS20 cells, in the presence of cyclic adenosine 3':5'-monophosphate (cAMP) phosphodiesterase inhibitor, responded to adenosine (200 muM) and 2-chloroadenosine (200 muM) with a 20-fold increase in intracellular cAMP levels. AMP (200 muM) additions caused only a 3.5-fold cAMP level elevation. ATP, ADP, guanosine, cytidine, uridine, and guanine, all at 200 muM, had no...
متن کاملPituitary adenylate cyclase-activating polypeptide (PACAP) stimulates adenylate cyclase and promotes proliferation of mouse primordial germ cells.
During migration and for about 2 days after their arrival in the gonadal ridges, primordial germ cells (the embryonic precursors of gametes of the adult animal) proliferate actively. Certain growth factors, such as stem cell factor and leukemia inhibitory factor, seem to be essential for survival, proliferation and possibly differentiation of mouse primordial germ cell in vivo and/or in vitro. ...
متن کاملDevelopment of a Mn-2+-sensitive, "soluble" adenylate cyclase in rat testis.
A distinctive Mn-2+-sensitive adenylate cyclase [ATP pyrophosphate-lyase(cyclizing), EC 4.6.1.1] system insensitive to fluoride has been found in rat seminiferous tubules and epididymal sperm. The development of this distinctive adenylate cyclase in testis was studied during spermatogenesis. It was first detectable in seminiferous tubules in immature rats at about the time of the first reductiv...
متن کاملProperties of an LH-stimulable adenylate cyclase in plasma membranes of interstitial cells from rat testis.
We studied the effect of guanyl nucleotides, divalent cations and luteinizing hormone (LH) on the regulation of adenylate cyclase (AC) in partially purified plasma membranes obtained from isolated interstitial cells of the rat testis. AC was activated to different degrees by guanosine triphosphate (GTP) and GMP-P(NH)P; the latter was about 10 times more active than the former. Enzyme activation...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1979
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod20.2.131